The Ponziani opening is rare and occurs in less than 1 in 100 games. From the data, you can expect that White will only have a 46.04% chance of winning, while Black should have a 53.96% chance of winning. Because of the fact that most players probably rarely see this opening, and that White has such a low expected chance of winning, it may be well worth it to keep this variation in your back pocket. Since if you are Black, you should have a significant edge and will probably catch your opponent off guard.